The S&M singer was chosen by the mag’s legendary editor, Anna Wintour, to star in the tenth anniversary of their ‘shape’ issue.
Shot by famed snapper Annie Leibovitz, the pic shows RiRi wearing a sheer dress embroidered with blue, green and red flowers.
Her scarlet hair is swept Jessica Rabbit-style across her face, standing out against the sea-blue background.
The Bajan beauty, 23, could barely contain her excitement about the shoot, breaking the news to fans on her Twitter feed back in January.
She wrote: “Just wrapped my first American Vogue cover shoot with Annie Leibovitz… Rah! #SEXY”