Tillie Mae Mawdsley and mum Michala – Tillie Mae Mawdsley, four, was diagnosed with degenerative disorder Sanfilippo syndrome. See MASONS story MNTRIAL; A mum and dad have launched a desperate bid to find a cure for the rare illness which is slowly turning their daughter into a human MANNEQUIN. Tillie Mae Mawdsley, four, was diagnosed with devastating degenerative disorder Sanfilippo syndrome two years ago. The toddler is one of just a handful of youngsters in the world missing an enzyme creating a build up of sugar around her muscles stiffening her joints. It means within just months the condition will leave her totally immobile unless someone else moves her arms and legs into position – just like a mannequins in a clothes store.